New Insights on Cause of Severe Reactions Following Pfizer/BioNTech mRNA COVID-19 Vaccination

COVID-19 Coronavirus Vaccine Injection

On the primary day of the UK marketing campaign for COVID-19 vaccination, there have been reviews of two circumstances of anaphylaxis — a extreme, probably life-threatening allergic response — inside minutes of administration of the Pfizer/BioNTech mRNA vaccine. Subsequently additional circumstances of suspected anaphylaxis to the Pfizer vaccine have been reported. A brand new report printed in Scientific & Experimental Allergy reveals that an allergy to the ingredient polyethylene glycol (PEG) is a trigger of anaphylaxis to the vaccine. Nevertheless, that is within the context of hundreds of thousands of doses safely administered.

The authors be aware that only a few persons are allergic to PEG, and so they present a information to figuring out those that are in danger. “This preliminary report confirms PEG as a trigger of anaphylaxis to the Pfizer/BioNTech vaccine, for the primary time,” they wrote. “COVID-19 vaccine anaphylaxis and PEG allergy are each uncommon, so proof of PEG because the trigger in a single case of vaccine anaphylaxis is vital. Nevertheless, it is very important emphasize that PEG allergy is uncommon and that COVID-19 vaccines stay secure.”

Reference: 7 April 2021, Scientific & Experimental Allergy.
DOI: 10.1111/cea.13874

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