A brand new examine from the College of Copenhagen revealed that consuming a weight loss program wealthy in antioxidants may very well counteract many of the well being advantages of train, together with diminished blood strain and ldl cholesterol in older males.
In older males, a pure antioxidant compound present in pink grapes and different crops – known as resveratrol – blocks many of the cardiovascular advantages of train. That is the shocking end result from a research project from the University of Copenhagen published today in The Journal of Physiology.
The analysis unusually means that consuming a weight loss program wealthy in antioxidants may very well counteract many of the well being advantages of train, together with diminished blood strain and ldl cholesterol.
Resveratrol has acquired widespread consideration as a doable anti-aging compound and is now broadly obtainable as a dietary complement; a lot has been made of its position in explaining the cardiovascular well being advantages of pink wine, and different meals.
In distinction to earlier research in animals during which resveratrol improved the cardiovascular advantages of train, this examine in people has offered shocking and powerful proof that in older males, resveratrol has the reverse impact.
New view on antioxidants
What’s rising is a brand new view that antioxidants are usually not the repair for every thing, and that a point of oxidant stress could also be needed for the physique to work appropriately. This pivotal examine means that reactive oxygen species, typically thought of as inflicting getting older and illness, could also be a needed sign that causes wholesome diversifications in response to stresses like train. So an excessive amount of of an excellent factor (like antioxidants in the weight loss program) may very well be detrimental to our well being.
“We studied 27 wholesome, bodily inactive males round 65 years previous for 8 weeks. Throughout the 8 weeks all of the males carried out high-intensity train coaching and half of the group acquired 250 mg of resveratrol day by day, whereas the different group acquired a placebo capsule (a capsule containing no lively ingredient). The examine design was double-blinded, thus neither the topics nor the investigators knew which participant that acquired both resveratrol or placebo”, says Ph.D. pupil Lasse Gliemann, College of Copenhagen, who was one of the researchers in the examine.
He continues: “We discovered that train coaching was extremely efficient in enhancing cardiovascular well being parameters, however resveratrol supplementation attenuated the constructive results of coaching on a number of parameters together with blood strain, plasma lipid concentrations and maximal oxygen uptake.”
“We had been shocked to search out that resveratrol supplementation in aged males blunts the constructive results of train coaching on cardiovascular well being parameters, partially as a result of our outcomes contradict findings in animal research”, provides professor Ylva Hellsten, the chief of the undertaking, and she or he continues: “It ought to be famous that the portions of resveratrol given in our analysis examine are a lot greater than what might be obtained by consumption of pure meals.
This analysis provides to the rising physique of proof questioning the constructive results of antioxidant supplementation in people.
Publication: Lasse Gliemann, et al., “Resveratrol Blunts the Positive Effects of Exercise Training on Cardiovascular Well being in Aged Males,” The Journal of Physiology, 2013; doi:10.1113/jphysiol.2013.258061
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