Study Shows Cannabis Reduces Headache and Migraine Pain by Nearly 50%

Study Shows Cannabis Reduces Headache and Migraine Pain by Nearly 50%

Inhaled hashish reduces self-reported headache severity by 47.3% and migraine severity by 49.6%, based on a current research led by Carrie Cuttler, a Washington State College assistant professor of psychology.

The research, published online on November 9, 2019, within the Journal of Pain, is the primary to make use of massive information from headache and migraine sufferers utilizing hashish in actual time. Earlier research have requested sufferers to recall the impact of hashish use up to now. There was one scientific trial indicating that hashish was higher than ibuprofen in assuaging headache, nevertheless it used nabilone, an artificial cannabinoid drug.

“We have been motivated to do that research as a result of a considerable variety of individuals say they use hashish for headache and migraine, however surprisingly few research had addressed the subject,” stated Cuttler, the lead creator on the paper.

Within the WSU research, researchers analyzed archival information from the Strainprint app, which permits sufferers to trace signs earlier than and after utilizing medical hashish bought from Canadian producers and distributors. The knowledge was submitted by greater than 1,300 sufferers who used the app over 12,200 instances to trace adjustments in headache from earlier than to after hashish use, and one other 653 who used the app greater than 7,400 instances to trace adjustments in migraine severity.

“We wished to method this in an ecologically legitimate approach, which is to have a look at precise sufferers utilizing whole-plant hashish to medicate in their very own houses and environments,” Cuttler stated. “These are additionally very massive information, so we are able to extra appropriately and precisely generalize to the larger inhabitants of sufferers utilizing hashish to handle these situations.”

Cuttler and her colleagues noticed no proof that hashish triggered “overuse headache,” a pitfall of extra standard therapies which may make sufferers’ complications worse over time. Nevertheless, they did see sufferers utilizing bigger doses of hashish over time, indicating they could be growing tolerance to the drug.

The research discovered a small gender distinction with considerably extra classes involving headache discount reported by males (90.0%) than by ladies (89.1%). The researchers additionally famous that hashish concentrates, reminiscent of hashish oil, produced a bigger discount in headache severity rankings than hashish flower.

There was, nonetheless, no important distinction in ache discount amongst hashish strains that have been increased or decrease in ranges of tetrahydrocannabinol (THC) and cannabidiol (CBD), two of probably the most generally studied chemical constituents in hashish, also referred to as cannabinoids. Since hashish is made up of over 100 cannabinoids, this discovering means that completely different cannabinoids or different constituents like terpenes might play the central position in headache and migraine reduction.

Extra analysis is required, and Cuttler acknowledges the restrictions of the Strainprint research because it depends on a self-selected group of people that might already anticipate that hashish will work to alleviate their signs, and it was not doable to make use of a placebo management group.

“I believe there are some slight overestimates of effectiveness,” stated Cuttler. “My hope is that this analysis will encourage researchers to tackle the tough work of conducting placebo-controlled trials. Within the meantime, this a minimum of provides medical hashish sufferers and their docs a little bit extra details about what they could anticipate from utilizing hashish to handle these situations.”

Reference: “Brief- and Lengthy-Time period Results of Cannabis on Headache and Migraine” by Carrie Cuttler, PhD; Alexander Spradlin, PhD; Michael J. Cleveland, PhD and Rebecca M. Craft, PhD, 9 November 2019, Journal of Pain.
DOI: 10.1016/j.jpain.2019.11.001

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