Vitamin B6 May Calm COVID-19’s Cytokine Storms and Unclog Blood Clots Linked to Lethality

Vitamin B6 might assist preserve COVID-19’s cytokine storms at bay.

Vitamin B6 might assist calm cytokine storms and unclog blood clots linked to COVID-19’s lethality. However analysis on it’s missing. A Hiroshima College professor calls on fellow scientists to research its potential position.

Who would have thought {that a} small fundamental compound like vitamin B6 within the banana or fish you had this morning could also be key to your physique’s strong response in opposition to COVID-19?

Research have up to now explored the advantages of nutritional vitamins D and C and minerals like zinc and magnesium in fortifying immune response in opposition to COVID-19. However analysis on vitamin B6 has been largely lacking. Meals scientist Thanutchaporn Kumrungsee hopes their paper printed in Frontiers in Vitamin could be step one in displaying vitamin B6’s potential in decreasing the chances of sufferers changing into critically ailing with the coronavirus. 

“As well as to washing your palms, meals and diet are among the many first strains of protection in opposition to Covid-19 virus an infection. Meals is our first drugs and the kitchen is our first pharmacy,” Kumrungsee, an affiliate professor at Hiroshima College’s Graduate Faculty of Built-in Sciences for Life, mentioned.

“Lately, many scientists have printed papers relating to the position of diets and vitamins within the safety in opposition to COVID-19. Nevertheless, only a few scientists are paying consideration to the vital position of vitamin B6,” she added.

Of their paper, she and her fellow researchers identified rising proof displaying that vitamin B6 exerts a protecting impact in opposition to power sicknesses corresponding to cardiovascular illnesses and diabetes by suppressing irritation, inflammasomes, oxidative stress, and carbonyl stress.

“Coronaviruses and influenza are among the many viruses that may trigger deadly lung accidents and loss of life from acute respiratory misery syndrome worldwide. Viral infections evoke a ‘cytokine storm,’ main to lung capillary endothelial cell irritation, neutrophil infiltration, and elevated oxidative stress,” they mentioned.

Kumrungsee defined that thrombosis (blood clotting) and cytokine storm (hyper irritation) could be carefully linked to the graveness of COVID-19. Cytokine storms occur when the immune system dangerously goes into overdrive and begins attacking even the wholesome cells. In the meantime, blood clots linked to COVID-19 can block capillaries, damaging important organs like the guts, lungs, liver, and kidneys.

Vitamin B6 is a recognized anti-thrombosis and anti-inflammation nutrient. Deficiency on this vitamin can also be related to decrease immune operate and larger susceptibility to viral infections.

“Vitamin B6 has an in depth relationship with the immune system. Its ranges at all times drop in folks below power irritation corresponding to weight problems, diabetes, and coronary heart illnesses. We will see from the information that overweight and diabetic persons are at excessive threat for COVID-19,” Kumrungsee mentioned.

“Thus, our try on this paper is to make clear the potential involvement of vitamin B6 in lowering the severity of COVID-19.”

The affiliate professor mentioned she is trying ahead to medical trials that might take a look at their speculation.

“It’s of nice curiosity to look at if vitamin B6 exerts safety in opposition to novel sorts of virus an infection and pneumonia which will probably be encountered sooner or later. At current, there may be few data relating to the protecting position of vitamins in opposition to pneumonia and lung illnesses,” she mentioned.

“After COVID-19, we must always develop the world of diet for lung illnesses corresponding to pneumonia and lung most cancers.”

Reference: “Potential Function of Vitamin B6 in Ameliorating the Severity of COVID-19 and Its Problems” by Thanutchaporn Kumrungsee, Peipei Zhang, Maesaya Chartkul, Noriyuki Yanaka and Norihisa Kato, 29 October 2020, Frontiers in Vitamin.
DOI: 10.3389/fnut.2020.562051


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